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Fig. 7 | Cancer Cell International

Fig. 7

From: Disulfidptosis-related signature predicts prognosis and characterizes the immune microenvironment in hepatocellular carcinoma

Fig. 7

Validation of the hub DRGs in HCC cell lines and functional analysis. A qPCR was used to analyze the mRNA expression of the protective and risk-related genes for disulfidptosis model in liver cancer cells. B Western blotting analyses of LCAT expression in liver cancer cell lines. C Western blotting analyses of LCAT expression in LM3 and Hep3B cell lines. D Migration was measured in LCAT-overexpressing LM3 and Hep3B cells. E Invasion was measured in LCAT-overexpressing LM3 and Hep3B cells. F Fluorescence staining of F-actin with phalloidin in vector and LCAT-OE LM3 cells treated with 5 μM BAY-876 or 1 mM TCEP for 18 h. G and H: The expression of LCAT in tumor tissues was significantly lower than that in adjacent nontumor tissues in HCC patients in the TCGA cohort G, and patients with higher LCAT expression demonstrated better survival outcomes H

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Cancer Cell International

ISSN: 1475-2867

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