Skip to main content
Fig. 5 | Cancer Cell International

Fig. 5

From: AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway

Fig. 5

BNIP3 was upregulated as autophagy promotor when AAA237 was administered. A–C Results from qRT-PCR results showed that AAA237 increased the expression of BNIP3 in a dose-dependent manner in U251. D–F Results from qRT-PCR results showed that AAA237 increased the expression of BNIP3 in a dose-dependent manner in LN229.The experiments were performed in triplicate, and the data are presented as mean ± SD, *P < 0.05, **P < 0.01 vs. control group. G Results of Western blot showed that the protein levels of BNIP3 were increased after treated with AAA237 in U251. H Results of Western blot showed that the protein levels of BNIP3 were increased after treated with AAA237 in U251

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us