Fig. 2

Stress granules form in A2780 cells under the treatment of PKI-402. A.A2780 cells were treated with PKI-402(2.5 μM) for 12 h and thapsigargin (Tg) 1 μM for 50 min. The colocalization of YB-1 and G3BP1 was determined by staining and observed by fluorescence microscopy, scale bar, 10 µm. B Colocalizations of YB-1 and G3BP1 in A were quantified using ImageJ software. C SKOV3 cells were treated as same as A2780 cells. D Colocalizations of YB-1 and G3BP1 in C were quantified using ImageJ software