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Fig. 9 | Cancer Cell International

Fig. 9

From: What role does GPR65 play in the progression of osteosarcoma? Its mechanism and clinical significance

Fig. 9

Analysis of downstream gene and signaling pathway regulating GPR65 in osteosarcoma cells. (A-B) Heatmap and Volcano plot shows differentially expressed genes in U2OS cells with or without GPR65 overexpression. (C-D) DO and GO enrichment analysis of DEGs in U2OS cells (Flag-GPR65 vs. NC). (E) Enriched chordal diagram of DEGs in U2OS cells. (F-G) KEGG enrichment analysis and Reactome annotations analysis of DEGs in U2OS cells. (H) GPR65-mediated Alternative Splicing (AS) events. (I) Protein-protein interactions (PPI) between DEGs in U2OS cells. (J) GSEA enrichment analysis of DEGs

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Cancer Cell International

ISSN: 1475-2867

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