What role does GPR65 play in the progression of osteosarcoma? Its mechanism and clinical significance

Table 2 Univariate and multivariate analysis of prognostic parameters in TARGET database overall survival

Variable	Univariate analysis	P-value	Multivariate analysis	P-value
Variable	HR (95% CI)	P-value	HR (95% CI)	P-value
GPR65 expression	0.775(0.623–0.965)	0.022	1.666(1.019–2.724)	0.042
Metastasis	0.25(0.13–0.482)	0	0.235(0.042–1.306)	0.098
FRT	0.998(0.997-0.0999)	0.001
Histologic response	0.2(0.045–0.88)	0.033	0.23(0.017–3.158)	0.271
EFS	0.997(0.996–0.998)	0	0.994(0.989–0.999)	0.009

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