Fig. 1
From: B cells in head and neck squamous cell carcinoma: current opinion and novel therapy
Different subtypes of B cells in the TME influence tumour growth through intercellular communication, cytokine secretion, etc. TLSs: tertiary lymphoid structures; GC: germinal centre; Tfh: follicular helper T cell; IL-21: interleukin-21; Bregs: regulatory B cell; TGF-β: transforming growth factor-β; IL-10: interleukin-10; IL-35: interleukin-35; Treg: regulatory T cell; INFγ: interferon γ; TIL-naive B: tumour infiltrating lymphocyte-naive B cell; PIGF: placental growth factor; PD-L1: programmed cell death-ligand 1; TNF: tumour necrosis factor