Fig. 1

Radiographic and histological images of MNOs and their parental tumors. A Magnetic resonance images, H&E staining, and IHC using antibodies against EMA and Ki67 in MNOs and their parental tumors [grade 1 (21-01, 22-01) and grade 2 (21-02, 21-03)]. Scale bars indicate 2 mm (left) and 20 μm (right) in parental tumors, and 100 μm (left) and 20 μm (right) in organoids. B Quantification of the expression levels of EMA and Ki67. Two-tailed Student’s t-test was conducted to evaluate statistical significance (*P < 0.05, **P < 0.01, ***P < 0.001)