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Fig. 4 | Cancer Cell International

Fig. 4

From: Single-cell N6-methyladenosine-related genes function within the tumor microenvironment to affect the prognosis and treatment sensitivity in patients with gastric cancer

Fig. 4

Identification of single cell m6A-related differentially expressed genes (SCMRDEGs). (A) Volcanic map for differentially expressed genes (DEGs) between normal and tumor tissues. (B) Venn diagram indicates overlapped SCMRDEGs between DEGs and single-cell m6A-related genes. (C) Heatmap of expression levels of DEGs in TCGA-STAD dataset. (D) GO analysis of 32 SCMRDEGs. (E) Delta area under the cumulative distribution function (CDF) curve. (F) Heatmap of clustering at consensus k = 3. (G) CDF curves of different consensus k-value. (H) Principle component analysis (PCA) of three clusters. (I) Immune infiltration of 22 immune cells in the three clusters. (J) Differences of immune checkpoints among three clusters

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Cancer Cell International

ISSN: 1475-2867

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