Fig. 2
Functions of circRAD23B in ovarian cancer cells. (A) qRT-PCR was used to verify the successfully establishment of circRAD23B overexpression and knockdown cell lines. (B) CCK-8 assay in HO8910 and A2780 cells transfected with circRAD23B shRNAs or pLV-circRAD23B. (C) Representative images of colony formation. (D) Statistical analysis of colony formation. (E) Representative images of EDU exprements. (F) Statistical analysis of EDU exprements. Red represents EDU staining, blue represents DAPI staining. (G) Apopotosis rate was analysed by flow cytometry after carboplatin treatment. (H) The IC50 of carboplatin in HO8910 and A2780 cells transfected with circRAD23B shRNAs or pLV-circRAD23B. Graph represents mean ± SD; *p < 0.05, **p < 0.01, and ***p < 0.001