Fig. 5

The immune landscape associated with pyroptosis in PTC. A Comparison of ESTIMATE scores between the PyroScore subgroups. B Association between the ESTIMATE scores and the PyroScore. C Lollipop plot shows the Spearman correlation between immune cell infiltration and the PyroScore. D Comparison of the ssGSEA enrichment scores of immune function pathways between the PyroScore subgroups. E Heatmap demonstrating the difference in the seven-step anticancer immunity cycle activity among the three PyroClusters. F Radar plot shows the difference in the ability of PyroClusters to recruit immune cells. G Spearman correlation between immunomodulators (co-inhibitors, co-stimulators and HLA molecules) and PRG signatures