Fig. 7

Clinical, internal and external validation of PRGs in PTC. A The mRNA expression levels of nine PRGs quantified by qRT‒PCR analysis in 20 pairs of clinical samples. B Internal validation of the mRNA expression of nine PRGs between 477 PTC and 59 NT from the entire TCGA cohort. C External validation of the mRNA expression of nine PRGs between 102 PTCs and 95 NTs from the GEO database (GPL570 sets). D Representative IHC staining images presenting the protein expression levels of nine PRGs in NT and PTC tissues from the HPA database. ×10: scale bar = 200 μm; ×40: scale bar = 50 μm