Fig. 2
From: Genome-wide CRISPR screen identifies ESPL1 limits the response of gastric cancer cells to apatinib
Enriched apatinib-resistant genes from the CRISPR/Cas9 activation screen in GC. a The Venn diagram showed 332 genes with sgRNA abundance greater than 1000 and sgRNA frequency greater than 1 in two replicate samples were selected for further analyses; b The top 10 enriched pathways by KEGG analysis; c The top 10 terms of molecular function, biological process and cellular component enriched in GO enrichment analysis; d The heatmap and bar graph showed the counts of resistant sgRNAs (left) and the sgRNA frequency (right) of the selected 7 genes; e Scatter plot showed sgRNAs targeting the intersected 332 genes in two replicate samples and the 7 candidate genes were marked