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Fig. 1 | Cancer Cell International

Fig. 1

From: Robust machine−learning based prognostic index using cytotoxic T lymphocyte evasion genes highlights potential therapeutic targets in colorectal cancer

Fig. 1

Genetic alterations and biological functions of CERGs in cancers. A The locations of CNVs in these genes on human chromosomes; B The findings revealed a pervasive trend with somatic copy number alterations manifesting at notably elevated frequencies, affecting a substantial portion of the samples across a wide spectrum of cancer types; C Most core CERGs exhibited distinct expression profiles in at least one cancer type; D DNA methylation patterns of core CERGs in the 20 cancer types; E Correlation between gene expression levels and DNA methylation status; F GO and KEGG analyses unveiled that these 31 genes predominantly participated in biological functions and pathways associated with the immune system

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Cancer Cell International

ISSN: 1475-2867

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