Skip to main content
Fig. 4 | Cancer Cell International

Fig. 4

From: The m6A methyltransferase METTL3 drives thyroid cancer progression and lymph node metastasis by targeting LINC00894

Fig. 4

METTL3 enhances LINC00894 mRNA stability through the M6A-YTHDC2-dependent pathway. A. Enrichment of METTL3-mediated LINC00894 m6A modification using meRIP-qPCR. B-C. Detection of LINC00894 expression in actinomycin D-treated PTC cells overexpressing METTL3 using qRT‒PCR. D. Displaying the binding site of YTHDC2 and LINC00894 using the AnnoLnc2 database. E. Analysis of the correlation between YTHDC2 and LINC00894 using the starBase database. F. Detection of LINC00894 expression using qRT‒PCR following YTHDC2 overexpression. H-I. Detection of LINC00894 expression levels in actinomycin D-treated PTC cells overexpressing YTHDC2 using qRT‒PCR. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us