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Fig. 3 | Cancer Cell International

Fig. 3

From: Signature construction and molecular subtype identification based on liver-specific genes for prediction of prognosis, immune activity, and anti-cancer drug sensitivity in hepatocellular carcinoma

Fig. 3

Different LSGs-based HCC subtypes presented differences in their stemness, aging and immune response levels. A–C Significant differences of LSGs score, stemness score, and aging score between HCC tumors and normal controls. D–F C1 HCCs presented lowest LSGs score while highest stemness score and aging score among the HCC subtypes. G The correlations between LSGs score and stemness score in HCC samples of different subtypes. H The correlations between LSGs score and aging score in HCC samples of different subtypes. I The significant positive correlation LSGs score and stemness score in HCC samples of different subtypes. J–L The expressional comparisons of MKI67, AFP, and ALB in HCC samples of different subtypes. M–O The comparisons of immune score, stromal score and tumor purity (negative correlated with estimate score) between HCC samples of different subtypes. P The heatmap of immune infiltrations in HCC samples of different subtypes. Wilcoxon test and Spearman correlation analyses were used and p < 0.05 was considered significant

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Cancer Cell International

ISSN: 1475-2867

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