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Fig. 5 | Cancer Cell International

Fig. 5

From: Signature construction and molecular subtype identification based on liver-specific genes for prediction of prognosis, immune activity, and anti-cancer drug sensitivity in hepatocellular carcinoma

Fig. 5

HCC subtype-related risk model and its correlations with HCC pathological features. A The tuning parameter lambda (λ) selection in LASSO Cox regression analysis using 10-fold cross-validation. B, C The risk model could effectively discriminate the 1-year, 2-year, and 3-year OS status of HCC patients in the training set (TCGA-HCC) and validation dataset (ICGC-HCC). D, E The independent prognostic effects of risk score in TCGA-HCC and ICGC-HCC datasets. F, G C1-HCCs presented the highest risk scores among all the HCCs in both TCGA-HCC and ICGC-HCC dataset. H, I The correlations of risk score with MKI67, CTLA4, PD1, and PD-L1 expressions in TCGA-HCC and ICGC-HCC samples

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Cancer Cell International

ISSN: 1475-2867

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