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Fig. 9 | Cancer Cell International

Fig. 9

From: Signature construction and molecular subtype identification based on liver-specific genes for prediction of prognosis, immune activity, and anti-cancer drug sensitivity in hepatocellular carcinoma

Fig. 9

Correlations of the key gene expressions with anti-cancer drug sensitivity in HCC cell lines. A–D Significant negative correlation of ADH4 expression with IC50s of anticancer drugs in HCC cell lines. E–H Significant negative correlation of PON1 expression with IC50s of anticancer drugs in HCC cell lines. I–L Significant negative correlation of PZP expression with IC50s of anticancer drugs in HCC cell lines. M Significant positive correlation of PON1 expression with IC50 of RAF265 in HCC cell lines. N–P Positive correlation trend of NR0B1 expression with IC50 values of PLX4720, Panobinostat, and Topotecan in HCC cell lines. IC50s, half maximal inhibitory concentrations. Spearman correlation analysis was used and p < 0.05 was considered as statistically significant

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Cancer Cell International

ISSN: 1475-2867

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