Fig. 10
From: ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway
ANGPTL4 upregulates c-Myc, Cyclin D1, and MMP2 expression via ERK1/2 pathway activation. A–C Western blot analysis of c-Myc, Cyclin D1, and MMP2 expression in OC cells transfected with si-ANGPTL4. *p < 0.05, **p < 0.01, ***p < 0.001, compared with si-NC. D–F Western blot analysis of c-Myc, Cyclin D1, and MMP2 expression in OC cells overexpressing ANGPTL4. PD98059 was used to inhibit ERK1/2 signaling. *p < 0.05, **p < 0.01, ***p < 0.001, compared with oe-ANGPTL4