Fig. 9
From: ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway
ERK inhibition abrogates growth and migration of ANGPTL4-overexpressing OC cells. A, B. CCK-8 cell proliferation assays were performed on OVCAR3 and A2780 cells in the oe-NC group, oe-ANGPTL4 group, and oe-ANGPTL4 + PD98059 group. C, D. Colony formation assay results of OVCAR3 and A2780 cells in oe-NC group, oe-AGPTL4 group, and oe-AGPTL4 + PD98059 group. E, F. The results of the Transwell migration assay were obtained for OVCAR3 and A2780 cells in the oe-NC group, oe-AGPTL4 group, and oe-AGPTL4 + PD98059 group.. Scale bar = 100 μm. *p < 0.05, **p < 0.01, ***p < 0.001, compared with oe-ANGPTL4