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Fig. 4 | Cancer Cell International

Fig. 4

From: A cuproptosis-related gene expression signature predicting clinical prognosis and immune responses in intrahepatic cholangiocarcinoma detected by single-cell RNA sequence analysis

Fig. 4

Association between CUPT score, tumor mutation burden (TMB) and somatic mutations. A–C Waterfall map showing the top 20 genes with the highest rates of mutations. D TP53 mutation frequencies in the high and low CUPT score group shown in a bar plot. E Differences in TMB between the high and low CUPT score patients (P = 0.0038). F Scatterplots displaying positive and negative correlations between CUPT score and TMB. G Kaplan–Meier curves demonstrating the difference in overall survival between TMB subgroups. H TMB and CUPT score stratified Kaplan–Meier curves demonstrating differences in overall survival

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