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Fig. 6 | Cancer Cell International

Fig. 6

From: A cuproptosis-related gene expression signature predicting clinical prognosis and immune responses in intrahepatic cholangiocarcinoma detected by single-cell RNA sequence analysis

Fig. 6

Gene set enrichment and potential predictive therapeutic value. A–C KEGG functional pathways enriched in the gene matrices of PLOD2, SLC39A4, and TNFAIP8 in the high and low CUPT score groups shown in multi-GSEA plots. Functional pathways enriched in gene matrices of the ICC patients in the high CUPT score group are represented by the curves above the X-axis while pathways enriched in low CUPT score ICC patients are represented by curves below the X-axis. D Correlation analysis of HALLMARK pathways. The upper triangle represents the correlation, and the lower triangle represents the coefficient. E Bar plot illustrating the correlation between CUPT score and drug sensitivity. F Dot plot showing the pathways targeted by medications correlated with the CUPT score

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