Fig. 4

Silencing hsa-circ-0013561 downregulates PDK3 expression but promotes miR-7-5p expression. A Proteomics analysis showcased the abnormal protein expression of metabolic pathways after silencet hsa_circ_0013561. B Bioinformatics analysis the downstream target of hsa-circ-0013561. C RT-qPCR detection show the expression of hsa-circ-0013561, miR-7-5p and PDK3. The data are expressed as the mean ± SD. *p < 0.05, ***p < 0.001 vs NC. All experiments were repeated three times