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Fig. 6 | Cancer Cell International

Fig. 6

From: The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization

Fig. 6

Ferroptosis inhibition promotes migration, invasion and EMT of AGS and MKN45 cells. A Representative results of wound healing assay in GPX4-overexpressed AGS and MKN45 cells after 24 h of incubation. The images show the extent of wound closure in the cells. Scale bar = 500 µm. The mean ± sd. is shown. **P < 0.01. B Migration and invasion assays were performed by the 24-transwell system. Scale bar = 500 µm. The mean ± sd. is shown. *P < 0.05, ***P < 0.001. C The expression of several key EMT markers Vimentin, E-Cadherin, N-Cadherin and ZO-1 were detected by western blotting of GPX4-overexpressed AGS and MKN45 cells

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Cancer Cell International

ISSN: 1475-2867

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