Fig. 2

ICA suppressed migration and invasion in TNBC cells. A–D After treatment with different concentrations (0, 12.5, and 25 µM) of ICA, wound healing of MDA-MB-468 and 4T1 cells was measured. B, D Analysis of the results of wound healing experiments on MDA-MB-468 and 4T1 cells. E, F After treatment with different concentrations of ICA, transwell invasion for MDA-MB-468 and 4T1 cells was measured. Bars represent the means ± SD of at least three independent experiments; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the control group (0 µM). ICA icariin, TNBC triple-negative breast cancer