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Fig. 2 | Cancer Cell International

Fig. 2

From: SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway

Fig. 2

SLC25A17 knockdown inhibited TNBC cell proliferation. A SLC25A17 mRNA and protein expression were higher in TNBC cell lines than in breast epithelial cell. B, C CCK8 and EdU assays were performed to evaluate the effect of SLC25A17 knockdown on proliferative capacity in MDA-MB-231 and MDA-MB-468 cells. D The apoptosis level was assessed by flow cytometric analysis in MDA-MB-231 and MDA-MB-468 cells. E Colony formation assays were performed to evaluate the proliferative capacity in MDA-MB-231 and MDA-MB-468 cells. F The expression levels of apoptosis-related and cell cycle-related proteins were detected by western blot. * p < 0.05, ** p < 0.01, *** p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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