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Fig. 3 | Cancer Cell International

Fig. 3

From: SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway

Fig. 3

SLC25A17 knockdown inhibited migration, invasion, and EMT of TNBC cells. A Representative transwell migration and invasion images and statistics for the number of migrated and invaded TNBC cells with SLC25A17 knockdown. (scale bar: 100 μm). B Representative pictures and quantitative data of wound healing assay in MDA-MB-231 and MDA-MB-468 with SLC25A17 knockdown. C Immunofluorescence staining analysis of EMT markers of E-Cadherin and Vimentin (red), and the nuclei were stained with DAPI (blue) (scale bar: 100 μm). D Invasion-related proteins, E-Cadherin, Vimentin, MMP9 and MMP2 were detected by western blot analysis. * p < 0.05, ** p < 0.01, *** p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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