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Fig. 6 | Cancer Cell International

Fig. 6

From: SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway

Fig. 6

ROS induced by SLC25A17 knockdown promoted apoptosis and autophagy in TNBC cells. A Flow cytometric analysis and quantification of ROS production in MDA-MB-231 and MDA-MB-468 cells. B The level of ROS was observed by fluorescence microscopy in SLC25A17 knockdown or overexpression MDA-MB-231 and MDA-MB-468 cells. (scale bar: 100 μm). C The protein levels of autophagy and apoptosis-related proteins was detected by western blot in MDA-MB-231 and MDA-MB-468 cells treated with or without NAC (5 mM). * p < 0.05, ** p < 0.01, *** p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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