Fig. 5

The growth of AML cells in vivo is suppressed upon knockdown of ANP32B. A Schematic of the in vivo experiment. B Relevant bioluminescence imaging of D20, D25 and D30 days in ANP32B knockdown group and control group. C Bioluminescent signal of liver, spleen and bone at the endpoint for each group. D Histogram displays the bioluminescence imaging values obtained from both groups of mice at various time intervals. E Histogram shows the bioluminescence imaging values of liver, spleen and bone. F Survival curves comparing both groups of mice. G H&E staining of organs from both groups of mice to assess their histological characteristics. H Representative IHC staining of Ki67 and C-MYC in liver tissue