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Fig. 1 | Cancer Cell International

Fig. 1

From: PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway

Fig. 1

PPP2R1B expression in CRC cells, CRC tissues and liver metastasis tissues. A The intersection genes between differential genes in GSE179979 dataset and 100 survival-related genes in TCGA database by Venny diagram. B High and low PPP2R1B expression plotted against overall survival time in 362 CRC patients in TCGA database. C mRNA expression of PPP2R1B in 100 pairs of CRC tissues and adjacent tissues by qRT-PCR. D Protein expression of PPP2R1B in CRC tissues, CRC liver metastasis and adjacent tissues by IHC. © mRNA expression of PPP2R1B in 5 CRC cell lines and 1 normal intestinal epithelial cells by qRT-PCR. F Protein expression of PPP2R1B in 5 CRC cell lines by WB. G Protein expression of PPP2R1B and p-ERK in 6 pairs of CRC and liver metastasis by WB. Bars indicate Mean ± SE, *P < 0.05, **P < 0.01 and ***P < 0.001 compared with the control

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