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Fig. 2 | Cancer Cell International

Fig. 2

From: Influential upregulation of KCNE4: Propelling cancer associated fibroblasts-driven colorectal cancer progression

Fig. 2

Identification of Key Genes and Establishment of Prognostic Models. (a) The intersection of TCGA-CRC tan and GSE17536 turquoise module genes was presented in the Venn diagram. (b, c). GO, KEGG analysis of the 75 genes. (d) Genes associated with overall survival in TCGA-CRC were screened using the univariate Cox analysis. (e) The two-gene prognostic signature was identified by Lasso–Cox regression analysis. (f) The construction of the CAF risk model. g, H. Kaplan-Meier analyses revealed that CRC patients in the high-CAF-risk group had poorer overall survival rates in both TCGA-CRC (g) and GSE17536 (h) cohorts

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