Fig. 3

Correlations Between CAF risk score and Infiltration, somatic variation, and drug response. (a) Spearman’s correlation analysis of CAF risk score with stromal scores and multi-estimated CAF infiltration. (b) Spearman’s correlation analysis of CAF markers with CAF risk score and two signature genes. (c) The top 20 mutational genes in low- and high-CAF-risk groups of TCGA-CRC. (d) Comparison of chemotherapy drug IC50 values between low- and high-CAF-risk Groups. (e, f). TIDE immunotherapy prediction analyses. (g) ROC curves of the CAF risk score in predicting immunotherapy responses in TCGA-CRC