Fig. 7
From: ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity
YAP reactivation weaken ACADL-mediated colony, migration inhibition and cycle arrest of NSCLC in vitro. a XMU-MP-1 application in ACADL overexpression cell could partly rescue the NSCLC colony ability according to the colony formation assay. b XMU-MP-1 application in ACADL overexpression cell could partly rescue the NSCLC invasive ability according to the transwell assay (Scale bar: 200 μm). c XMU-MP-1 application in ACADL overexpression cell could partly rescue the expression of cyclin B1, cyclin D1, abolished the positive effect on P27 and P21 of ACADL as the results of western blot. * vs. Control with DMSO group; * P < 0.05; ** P < 0.01; *** P < 0.001. # vs. ACADL with DMSO group; #P < 0.05; ##P < 0.01; ###P < 0.001. ACADL: Acyl-CoA dehydrogenase long chain. YAP: Yes-associated protein. NSCLC: Non-small cell lung cancer