Fig. 7

In vivo experiment corroborating the role of TMEM176B in GC progression. A, B Tumorigenesis was compared between the control and TMEM176B knockdown groups. C, D Differences in tumor volume and mass between control and TMEM176B knockdown groups were measured. E, F WB determined the expression levels of ASNS and proteins related to the PI3K-Akt-mTOR signaling pathway in the control and TMEM176B knockdown groups. G IHC and H&E staining were used to compare proliferation and apoptosis between the control and TMEM176B knockdown groups. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001