Cancer Cell International

Table 1 Correlation of TMEM176B expression with clinicopathologic parameters in GC patients

From: Transmembrane protein 176B regulates amino acid metabolism through the PI3K-Akt-mTOR signaling pathway and promotes gastric cancer progression

Parameters	Cases	TMEM176B expression		χ²	P-Value
Parameters	Cases	Low	High	χ²	P-Value
Gender				0.045	0.833
Male	71	39	32
Female	36	19	17
Age(years)				0.448	0.503
< 61	43	25	18
≥ 61	64	33	31
Tumor location				0.045	0.833
Upper	36	19	17
Middle + lower	71	39	32
Tumor size(cm)				9.696	0.002^a
< 6	48	34	14
≥ 6	59	24	35
Depth of invasion				5.313	0.021^a
T1 + T2	29	21	8
T3 + T4	78	37	41
Lymph node metastasis				4.584	0.032^a
Absent	23	17	6
Present	84	41	43
Differentiation				7.313	0.007^a
Well + moderate	41	29	12
Poor	66	29	37
TNM stage				5.388	0.020^a
I + II	34	24	10
III + IV	73	34	39

^aStatistically significant (p < 0.05)

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ISSN: 1475-2867

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