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Fig. 1 | Cancer Cell International

Fig. 1

From: RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway

Fig. 1

Elevated expression of RGS20 is associated with a poor prognosis for NSCLC A The mRNA expression of rgs20 in many cancers was assessed using TCGA database. B The representative IHC staining of the RGS20 protein in lung adenocarcinoma tumors (red arrow) and adjacent non-cancerous tissues (green arrow). C The quantitative analysis of IHC staining results for RGS20 in 126 LUAD tissues. D The representative IHC staining of RGS20 protein in lung squamous carcinoma tissue microarray (red arrow) and adjacent non-cancerous tissues (green arrow). E The quantitative analysis of IHC staining results for RGS20 in 75 LUSC tissues. Kaplan-Meier analysis of the association between RGS20 protein levels and overall survival in 126 LUAD (F) and 75 LUSC (G) patients. The results in C and E were quantified with CaseViewer (version 2.3) and presented as H-Scores. The samples from patients were divided into high and low subgroups based on the median H-score of IHC staining, which represents the expression level of RGS20. * p < 0.05, **p < 0.01, ***p < 0.001

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