Table 2 Possible therapeutic targets related to energy metabolism

NDUFA4

[25, 32, 33, 38, 42, 43]

Response gene to complement 32 protein (RGCC)

[64]

Cepharanthine (CEP)

[65]

The muscle isoform of pyruvate kinase PKM2

[66]

Homocysteine-inducible ER protein with ubiquitin-like domain 1 (HERPUD1)

[67]

Dibenzyl diselenide (DBDS) and statins

[68]

Histone methyltransferase, suppressor of variegation 3–9 homolog 1 (SUV39H1)

[69]

A part of the cytoplasmic protein complex Lsm1-7-Pat1 (LSM1)

[70]

Euphorbia factor L1 (EFL1)

[71]