The molecular characteristics could supplement the staging system of pT2/T3N0M0 esophageal squamous cell carcinoma: a translational study based on a cohort with over 20 years of follow-up

Table 1 The baseline information of esophageal squamous cell carcinoma

	Molecular score		\({\varvec{\upchi }}^{2}\)	p-value
	Low (n = 105)	High (n = 121)	\({\varvec{\upchi }}^{2}\)	p-value
Sex			0.003	0.954
Male	76(72.4%)	88(72.7%)
Female	29(27.6%)	33(27.3%)
Age			2.244	0.134
<=65	86(81.9%)	89(73.6%)
> 65	19(18.1%)	32(26.4%)
Tumor location			0.672	0.715
Upper	10(9.5%)	15(12.4%)
Middle	70(66.7%)	81(66.9%)
Lower	25(23.8%)	25(20.7%)
Surgical approach			6.001	0.423*
Sweet	76(72.4%)	93(76.8%)
Two incisions in the left chest	4(3.8%)	1(0.8%)
Ivor-Lewis	3(2.9%)	5(4.1%)
McKeown	22(20.9%)	22(18.3%)
Examined lymph nodes			0.009	0.924
≤ 6	54(51.4%)	63(52.1%)
> 6	51(48.6%)	58(47.9%)
Tumor grade			8.489	0.014
Grade I	33(31.4%)	24(19.8%)
Grade II	55(52.4%)	59(48.8%)
Grade III	17(16.2%)	38(31.4%)
Tumor length (cm)			0.017	0.897
≤ 5	72(68.6%)	82(67.8%)
> 5	33(31.4%)	39(32.2%)
pT			0.093	0.760
T2	42(40.0%)	46(38.0%)
T3	63(60.0%)	75(62.0%)

*This comparison was based on the Fisher’s exact test. Other comparisons were based on the Chi-square test

ISSN: 1475-2867