Table 3 Univariable and multivariable analyses for the cohort

Sex

Male

1

Reference

1

Reference

Female

0.754

0.530–1.074

−0.282

0.118

0.734

0.505–1.068

−0.309

0.106

Age

≤ 65

1

Reference

1

Reference

> 65

1.344

0.947–1.908

0.296

0.098

1.245

0.851–1.820

0.224

0.259

Surgical approach

Sweet

1

Reference

Two incisions in the left chest

0.880

0.325–2.384

−0.128

0.802

Ivor-Lewis

1.394

0.650–2.990

0.332

0.393

McKeown

1.203

0.819–1.767

0.184

0.347

Examined lymph nodes

≤ 6

1

Reference

> 6

0.936

0.691–1.269

−0.066

0.671

Tumor location

Upper

1

Reference

1

Reference

Middle

0.697

0.433–1.124

−0.360

0.139

0.640

0.393–1.042

−0.446

0.073

Lower

0.688

0.400–1.184

−0.373

0.177

0.594

0.342–1.032

−0.521

0.064

Tumor grade

Grade I

1

Reference

0.081

1

Reference

Grade II

1.024

0.698–1.500

0.023

0.904

0.923

0.627–1.359

−0.098

0.686

Grade III

1.495

0.977–2.289

0.402

0.064

1.219

0.785–1.892

0.165

0.377

Tumor length (cm)

≤ 5

1

Reference

> 5

1.014

0.733–1.402

0.014

0.934

pT

T2

1

Reference

1

Reference

T3

1.421

1.032–1.957

0.352

0.031

1.328

0.960–1.837

0.283

0.087

Molecular Score

Low

1

Reference

1

Reference

High

3.393

2.432–4.734

1.222

< 0.001

3.263

2.321–4.586

1.183

< 0.001