Fig. 1
The levels of N6-methyladenosine (m6A) in RNA of the peripheral blood of healthy controls (HCs) and patients with colorectal cancer (CRC). A The m6A levels of peripheral blood RNA in HC (n = 44) and patients with CRC (n = 78); B m6A levels in peripheral blood RNA of patients with different clinical stages of CRC (stage I, n = 13; stage II, n = 20; stage III, n = 31; stage IV, n = 12); C the m6A levels of peripheral blood RNA in patients with CRC (n = 8) before surgery and after seven days of surgery; D comparison of m6A levels in peripheral blood RNA between patients with CRC with (n = 16) and without (n = 56) metastasis. The bars represent the mean ± standard deviation (SD) of the results from three replicate measurements; *P < 0.05, ****P < 0.0001. HC: healthy control, CRC: colorectal cancer