Fig. 3

Performances of POSTN in early chemotherapy efficacy monitoring of BCa. A–C, agreement between radiographic response and markers’ response in 58 cases. Radiographic response was measured according to RECIST, version 1.1. Dotted lines indicated a 20% decrease or increase of markers. Agreement levels was evaluated by Cohen's weighted (Fleiss-Cohen weights) kappa coefficient. D–F, change rate of three markers was calculated by dividing the change level by the baseline level in cases with PR (n = 33) and Non-PR (n = 25) response. Dotted lines indicated decrease or increase of markers. G, comparison of consistent rate of three markers in cases with PR response. Dotted lines indicated a 20% decrease of markers. H, consistent frequency comparison among three markers in cases with partial response. PR partial response, SD stable disease, PD progressive disease