Fig. 1
From: The upregulation of VGF enhances the progression of oral squamous carcinoma
Upregulation of VGF in HNSCC and OSCC. (A) Analysis of pan-malignancies in TCGA database using TIMER algorithm. Upregulation of VGF transcript in the vast majority of paired malignancies is noted. (B) TCGA HNSCC data. Lt, upregulation of VGF in tumors. Middle, a reverse correlation lies between VGF expression and NUMB expression. Rt, Kaplan-Meier survival curve illustrating an association between high VGF expression and worse patient survival. (C) Our OSCC cohort data. Lt, upregulation of VGF in tumors. Middle, VGF expression as related to clinicopathologic parameters. Rt, Kaplan-Meier survival curve illustrating an association between high VGF expression and worse patient survival. Medium TPM values of VGF in HNSCC or OSCC tumors are used as a cutoff to designate high or low expression in VGF