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Fig. 3 | Cancer Cell International

Fig. 3

From: LncRNA RASAL2-AS1 promotes METTL14-mediated m6A methylation in the proliferation and progression of head and neck squamous cell carcinoma

Fig. 3

Overexpression of RASAL2-AS1 restored the proliferation inhibition of HNSCC cells induced by silencing METTL14. (A) Levels of m6A in HNSCC cells (including SCC-15, SCC-25 and Cal-27) were detected by m6A Dot blot. (B) The optimal sequence of METTL14 silencing efficiency. The expressions of METTL14 mRNA (C), (D) the cell viability, (E) colony formation ability, (F) migration ability, (G) scratch area and (H) cell cycle after co-transfected overexpression vector RASAL2-AS1 and silenced METTL14 in Cal-27 and SCC-25 (scale bars, 500 μm). *p < 0.05, **p < 0.01

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