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Fig. 6 | Cancer Cell International

Fig. 6

From: LncRNA RASAL2-AS1 promotes METTL14-mediated m6A methylation in the proliferation and progression of head and neck squamous cell carcinoma

Fig. 6

RASAL2-AS1 promotes HNSCC cell proliferation and growth by targeting METTL14 in vivo. (A) Xenograft plots in BALB/c mice by inoculating the right axilla with pcDNA3.1, pcDNA3.1 RASAL2-AS1, and pcDNA3.1 RASAL2-AS1 + si-METTL14 cotransfected SCC-25 cells, respectively. (B) Plots show xenograft tumors excised from mice on day 40. (C) Determination of each group of tumor volumes of nude mouse xenograft tumors at different days (n = 6 for each group). (D) Representative images of IHC staining of the expression of METTL14 and LIS1 in HNSCC tissues are shown (Original magnification ×200 scale bars, 25 μm; ×400 scale bars, 12.5 μm). *p < 0.05, **p < 0.01

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