Fig. 6
From: Low TYROBP expression predicts poor prognosis in multiple myeloma
TYROBP is lowly expressed in multiple myeloma and overexpression of TYROBP promotes myeloma cells adhesion and inhibits their migration. A RT-PCR conducted to analyze the mRNA expression of TYROBP. B Western blot was employed to determine the expression level of TYROBP in multiple myeloma. C TYROBP overexpression determined by Western blot in U266 and RPMI8226 cells. D RT-PCR revealing the successful up-regulation of TYROBP. E Adhesion assay suggesting that TYROBP facilitated the adhesion of U266 and RPMI8226 cells. F Transwell migration assay proving that TYROBP overexpression inhabited the migration of U266 and RPMI8226 cells. *p < 0.05, **p < 0.01 and ***p < 0.001