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Fig. 1 | Cancer Cell International

Fig. 1

From: Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer

Fig. 1

CAF heterogeneity and function in prostate cancer (PCa). (A) Western blot analysis for FAP, PDGFRα/β, α-SMA and GAPDH in the NFs (Normal fibroblasts) and CAFs (cancer-associated fibroblasts). (B) Transwell assay of PC-3 and DU145 cell migration mediated by CAF culture supernatant. (C) CCK-8 assessment of PC-3 and DU145 cell proliferation mediated by CAF culture supernatant. (D) Heatmap of differentially expressed genes (DEGs) in paired NFs and CAFs. (E) T-SNE plot of single cells from CAFs in PCa tissues. (F) Heatmap shows the marker genes of s distributed in the 12 clusters.

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Cancer Cell International

ISSN: 1475-2867

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