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Fig. 3 | Cancer Cell International

Fig. 3

From: Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer

Fig. 3

The tCAF score model and association with survival, clinical features and drug sensitivity in PCa. (A) Kaplan-Meier analysis of the tCAF score low and high groups in TCGA, MSKCC and CPGEA PCa cohorts. (B) ROC curves of tCAF scores at 3, 5, and 7 years in the TCGA cohorts. (C) GSVA enrichment analysis showing the activation states of biological pathways in the tCAF score low and high groups. (D-E) Differences in clinical characteristics between the tCAF score low and high groups in the TCGA PCa cohort. (F) The effect of tCAF scores on response to commonly used drugs. (G) The 3D structure tomographs of 5 candidate small-molecule drugs for tCAF score high groups in PCa.

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Cancer Cell International

ISSN: 1475-2867

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