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Fig. 3 | Cancer Cell International

Fig. 3

From: High LGALS3 expression induced by HCP5/hsa-miR-27b-3p correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma

Fig. 3

Identification of hsa-miR-27b-3p as a potential upstream miRNA of LGALS3 in HCC. (A) Candidate miRNAs interacting with LGALS3 mRNA established by Cytoscape software. (B) Correlation analysis between LGALS3 expression and predicted miRNAs in HCC based on the ENCORI database. (C) The expression of hsa-miR-27b-3p and hsa-miR-128-3p in HCC and corresponding normal tissues analyzed by ENCORI database. (D) qRT-PCR analysis of hsa-miR-27b-3p expression in tumor and adjacent normal tissues from 5 HCC patients. The differential expression of hsa-miR-27b in HCC with various tumor stages (E) and tumor grades (F) assessed by UALCAN. (G) Schematic representation of the hsa-miR-27b-3p target sequence within the 3′UTR of LGALS3. **p value < 0.01; ***p value < 0.001

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