Fig. 8

The correlation between LGALS3 or HCP5 and pathway score in HCC analyzed by Spearman method. The abscissa represents the expression of LGALS3 or HCP5 gene, and the ordinate represents the pathway score of this gene in HCC. The red curve represents the density distribution of LGALS3 or HCP5 gene, and the blue curve represents the distribution of pathway score. The positive correlation between LGALS3 or HCP5 and pathway score are given (|r| >0.2, p value < 0.05, n = 371). Ten pathways are included: (A) tumor inflammation signature; (B) inflammatory response; (C) IL-10 anti-inflammatory signaling pathway; (D) cellular response to hypoxia; (E) ECM-related genes; (F) apoptosis; (G) PI3K/AKT/mTOR pathway; (H) P53 pathway; (I) degradation of ECM; (J) ferroptosis