Fig. 6

CCDC25 inhibits tumor growth and promotes apoptosis A Images of xenograft-transplanted nude mouse models (n = 6) and dissected tumor 14 days after injection with overexpressed CCDC25 786–0 cells and their corresponding NC cells. B Xenograft tumor growth volume curves of OE-CCDC25 cells and their corresponding NC cells. C Xenograft tumor weight curves of OE-CCDC25 cells and their corresponding NC cells. D Representative fluorescence images of Xenograft tumor labeled by DAPI, CCDC25, ITGA3. Scar bar, 100 μm. N = 6. E Xenograft tumor tissues were stained by IHC using ki-67 antibodies. The scale bar represents 100 μm. F H&E and fluorescence images of Xenograft tumor labeled by DAPI, Tunel, Caspase3