Fig. 3From: Significance of PSCA as a novel prognostic marker and therapeutic target for cancerProposed mechanism for regulation and function of PSCA by slug in NPC incidence. The binding of the slug to PSCA promoter causes PSCA downregulation and consequently N-cadherin and ZEB1/2 increase. These changes activate Roh A, which initiates the EMT induction process and causes nasopharyngeal cancerBack to article page